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Oklahoma State University
Center for Veterinary Health Sciences

Healthy Animals - Healthy People

Lara Maxwell

Department of Physiological Sciences
Dr. Lara Maxwell, DVM, PhD, DACVCP
Associate Professor

264 McElroy Hall
Stillwater, OK 74078

Research Interests

Dr. Maxwell works on disparate topics, ranging from anticancer to antiviral drugs. However, these diverse lines of inquiry do fit within the unifying theme of her research: improving patient outcomes through pharmacokinetic and pharmacodynamic modeling. At its simplest, pharmacodynamic data reveal the actions of a xenobiotic on a pharmacological target, such as a receptor or a pathogen. The field of pharmacokinetics is closely related to xenobiotic disposition, but provides a mathematical description of the time course of xenobiotic movement through the body. Pharmacokinetic and pharmacodynamic modeling are most powerful when combined, as their union increases the odds of successfully predicting the actions of a xenobiotic as a function of both concentration and time. She uses classical compartmental or noncompartmental, physiologically based, and population pharmacokinetic modeling. Dr. Maxwell agrees with the axiom that “the dose makes the poison”, so she enjoys both pharmacological and toxicological applications of xenobiotic modeling.